Immunosuppressant-Induced Acneiform Eruption of the Breast

Acneiform eruptions are dermatoses that resemble true acne. They are almost always drug induced (Indian J Dermatol Venereol Leprol 2009;75:255). Unlike true acne, acneiform eruptions have sudden onset, widespread involvement, occur in unusual locations, occur beyond typical acne age, consist of monomorphous lesions, and clear after the offending drug has been discontinued. The most common culprits are corticosteroids, iodides, bromides, anticonvulsants, Isoniazid (Acta Derm Venereol Suppl (Stockh) 1975;74:119), and immunosuppressants. We present a case of immunosuppressant-induced acneiform eruption of the breast in a 36-year-old female renal transplant recipient. To our knowledge, this is the first description of this condition appearing in the breast. Both the mammographic and ultrasound features will be described.