Biological Rhythms in Clinical Practiceis an interesting book that deals with time-related variations in human biology and the effects of these regular repetitions on a number of processes in human behavior, physiology, and pathology. It is indicated that the study and awareness of the rhythmic biological processes can allow the practicing physician to enhance the patient's response to treatment and the community to improve the well-being and productivity of a large group of its citizens. Although the authors describe and emphasize circadian rhythms (24-hour periods), they also present circannual (seasonal period) and ultradian (short period) rhythms. An effort has been made to explain the endogenous components andZeitgebers(time-givers) and the exogenous components that can alter or influence biological rhythms. Chronopharmacology, "time-dependent variations in pharmacology," is well presented, and its implications in pharmacokinetics and pharmacodynamics in health and disease are given in some detail. The importance of biological rhythms
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Panayotis G. Iatridis (1990) studied this question.