Marked Eosinophilia With Cancer: A Poor Prognostic Sign

Case Reports1 July 1951MARKED EOSINOPHILIA WITH CANCER: A POOR PROGNOSTIC SIGNIRVING B. BRICK, M.D., LEWIS GLAZER, M.D.IRVING B. BRICK, M.D.Search for more papers by this author, LEWIS GLAZER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-1-213 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere are many causes of eosinophilia. Wintrobe1has listed and discussed the diverse conditions in which eosinophilia appears. However, only the following lines referable to cancer appear in this textbook about a miscellaneous group of disorders in which eosinophilia occurs: "Tumours of the ovary, various other neoplasms, especially those involving serous surfaces or bones or when necrosis of tumour tissue occurs." Scant attention to this finding in cancer was given in the American literature until the appearance of the report by Isaacson and Rapoport2in 1946. They collected from the literature 19 cases of pronounced eosinophilia with cancer (over 10...Bibliography1. Wintrobe MM: Clinical hematology, 2nd Ed., 1946, Lea and Febiger, Philadelphia, pp. 172-175. Google Scholar2. IsaacsonRapoport NHP: Eosinophilia in malignant tumors: its significance, Ann. Int. Med. 25: 893-902 (Dec.) 1946. LinkGoogle Scholar3. BernardMarieAnchel LJL: Cancer primitif du poumon avec éosinophilie, pleurale et sanguine, Bull. et mém. Soc. méd. d. hôp. de Paris 47: 1610-1614, 1931. Google Scholar4. StickneyHeck JMJJ: The clinical occurrence of eosinophilia, M. Clin. North America 28: 915-919 (July) 1944. CrossrefGoogle Scholar5. HarvierPestelMarche PMJ: Cancer secondaire du foie avec grande eosinophilie sanguine, Bull. et mém. Soc. méd. d. hôp. de Paris 63: 261-264, 1947. MedlineGoogle Scholar6. Rebuck JW: The functions of the white blood cells, Am. J. Clin. Path. 17: 614-630 (Aug.) 1947. CrossrefMedlineGoogle Scholar7. Samter M: The response of eosinophiles in the guinea pig to sensitization, anaphylaxis and various drugs, Blood 4: 217-246 (March) 1949. CrossrefMedlineGoogle Scholar8. ForshamThornPruntyHills PHGWFTAG: Clinical studies with pituitary adrenocorticotropin, J. Clin. Endocrinol. 8: 15-66 (Jan.) 1948. CrossrefMedlineGoogle Scholar9. Lanier PF: Sternal marrow in patients with metastatic cancer, Arch. Int. Med. 84: 891-906 (Dec.) 1949. CrossrefGoogle Scholar10. Gill AJ: Local eosinophilia in malignant neoplasms, J. Lab. and Clin. Med. 29: 820-824, 1944. Google Scholar11. Biggart JH: Some observations on the eosinophile cell, J. Path. and Bact. 35: 799-816, 1932. CrossrefGoogle Scholar12. Atmar RC: Familial eosinophilia, J. A. M. A. 115: 449-450 (Aug. 10) 1940. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 10, 1950.From Captain John B. Adams Hospital, Soldiers Home, Chelsea, Massachusetts, and the Department of Medicine, Georgetown University School of Medicine, Washington, D.C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEosinophilia and Lung Cancer: Analysis From Real-World Data and Mendelian Randomization StudyHypereosinophilia in Solid Tumors—Case Report and Clinical ReviewInterleukin-5 Facilitates Lung Metastasis by Modulating the Immune MicroenvironmentTissue Eosinophilic InfiltrationEosinophilia and Uterine LeiomyosarcomaBlood eosinophilia in hodgkin's disease: A follow-up of 25 cases in VenezuelaEosinophilia in squamous cell carcinoma of the oral cavity, external genitalia and anus?clinical correlationsTumour-associated eosinophilia: a review.Metastatic carcinoma simulating agnogenic myeloid metaplasia and myelofibrosisTHE SYNDROME OF HYPONATREMIA AND RENAL SODIUM LOSS PROBABLY RESULTING FROM INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE*H. J. ROBERTS, M.D. 1 July 1951Volume 35, Issue 1Page: 213-218KeywordsBoneEosinophiliaHospital medicineNecrosisOvaries ePublished: 1 December 2008 Issue Published: 1 July 1951 PDF downloadLoading ...