Key result
Amoxapine may induce rapidly reversible neuroleptic malignant syndrome, particularly in older patients.
Amoxapine, a second-generation antidepressant, can induce neuroleptic malignant syndrome, a risk that may be higher in older patients.
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May warrant NMS monitoring with amoxapine in older adults; single case leaves open incidence and susceptibility confirmation.
Sudhakar Madakasira (1989) studied this question. Amoxapine treatment can induce neuroleptic malignant syndrome, an adverse reaction that resolves rapidly upon drug discontinuation and may pose a particular risk to older patients.
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