Key result
Smoking history or continued smoking after heart transplantation significantly increases the risk of perioperative complications, graft rejection, and decreased survival.
Why the study?
Does a history of smoking or continuing to smoke increase the risk of complications and decreased survival in recipients of orthotopic heart transplants?
Does a history of smoking or continuing to smoke increase the risk of complications and decreased survival in recipients of orthotopic heart transplants?
Smoking history or continuation after heart transplantation significantly increases the risk of complications, graft rejection, and mortality.
Reinforces pre-transplant smoking cessation counseling; leaves open prospective trials to quantify intervention benefits on outcomes.
Recipients of orthotopic heart transplants who have a history of smoking or who continue to smoke following transplantation have a significantly increased risk for perioperative complications, graft rejection, and decreased survival because of the development of aggressive lung cancers and accelerated graft coronary artery disease.
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Collins et al. (1999) studied this question. Smoking history or continued smoking after heart transplantation significantly increases the risk of perioperative complications, graft rejection, and decreased survival.
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