Angiogenesis Therapy Moves beyond Cancer

Current Clinical Issues20 July 2004Angiogenesis Therapy Moves beyond CancerJennifer Fisher WilsonJennifer Fisher WilsonSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-2-200407200-00027 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Doctors in different subspecialties, have, over the years, learned that people with Down syndrome have unsurpassed protection against certain diseases. Cancer is almost unheard of among people with this syndrome, according to oncologists. Noncongenital heart problems rarely afflict this population, according to cardiologists. And diabetic retinopathy never develops among people with both Down syndrome and diabetes, according to endocrinologists. But, until recently, most doctors only knew that Down syndrome provided protection; they did not know why.They knew that people with Down syndrome had 3 copies of chromosome 21 (trisomy 21), but no one made the link between the extra ... Author, Article, and Disclosure InformationAffiliations: Disclosures: None disclosed.E-mail:[email protected]org. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByImmune Surveillance in Health and Diseases of Aging: Definitions of Acute and Chronic Inflammation [Yin and Yang]Complete remission of psoriasis following bevacizumab therapy for colon cancerTargeting tumor vascular endothelium: an emerging concept for cancer therapyRole of VEGF in maintaining renal structure and function under normotensive and hypertensive conditionsMethylnaltrexone inhibits opiate and VEGF-induced angiogenesis: Role of receptor transactivationAngiogenesis as a Novel Component of Inflammatory Bowel Disease PathogenesisAngiogénesis en la psoriasisFacts and Ideas from Anywhere 20 July 2004Volume 141, Issue 2Page: 165-168KeywordsAngiogenesisBlood vesselsCardiovascular therapyDown syndromeDrugsEye diseasesGrowth factorsMacular degenerationProteinsVascular endothelial growth factor ePublished: 20 July 2004 Issue Published: 20 July 2004 CopyrightCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...