Key result
Histologic and immunohistochemical examination of a Pacinian corpuscle in the pancreas of a 76-year-old woman with pancreatic cancer demonstrated immunoreactivity for neurofilament protein, neuron-specific enolase, S-100 Protein, and four cytochrome P450-isozymes.
Case Report (n=1)
Reports the rare finding and immunohistochemical profile of a Pacinian corpuscle in the human pancreas.
Incidental pancreatic Pacinian corpuscles warrant no clinical action; extends sparse immunohistochemical data on human visceral innervation.
During our systematic examination of the distribution of cytochrome P450 enzymes in the normal and diseased human pancreas, we observed a Pacinian corpuscle in a serial section of a tissue from a pancreatic cancer patient. We report the histologic and immunohistochemical patterns in this corpuscle and review the literature. The Pacinian corpuscle was situated within the pancreas of a 76-year-old woman with cancer in the head of the pancreas. We could demonstrate immunoreactivity within the corpuscle for the neurofilament protein. neuron-specific enolase, S-100 Protein, and for four cytochrome P450-isozymes. The possible function of Pacinian corpuscles in the mammalian and human pancreas is discussed.
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Standop et al. (2001) conducted a case report in Pancreatic cancer (n=1). Histologic and immunohistochemical examination was evaluated on Immunoreactivity within the corpuscle. Histologic and immunohistochemical examination of a Pacinian corpuscle in the pancreas of a 76-year-old woman with pancreatic cancer demonstrated immunoreactivity for neurofilament protein, neuron-specific enolase, S-100 Protein, and four cytochrome P450-isozymes.
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