An ADP‐ATP exchange reaction was studied in NaI‐treated microsomes from rat brain. At low concentrations of MgCl2 a nucleotide exchange reaction, elicited in the presence of Na+, had an absolute specificity for ATP. The reaction was stimulated by oligomycin and inhibited by ouabain and EDTA. It is probable that this Na+‐stimulated ADP‐ATP exchange reaction is a component of the Na‐K ATPase system.
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Wilhelm Stahl (1968) studied this question.
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