Key result
Negative feedback pump regulation converts chaotic vasomotion to periodic or steady-state behavior in ~60% of cases.
Vascular chaos in isolated resistance arteries can be externally controlled via negative feedback, suggesting potential physiological and pathophysiological regulatory mechanisms.
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External feedback may regularize chaotic vasomotion in isolated arteries; leaves open in vivo relevance and any clinical translation.
Griffith et al. (1995) studied Chaotic vasomotion. Negative feedback loop regulating pump speed was evaluated on Conversion to periodic or steady-state behavior. A negative feedback loop regulating pump speed converted irregular chaotic vasomotion to periodic or steady-state behavior in approximately 60% of cases, with a fall in fractal dimension.
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