Asymmetric Allylsilane Additions to Enantiopure N-Acylhydrazones with Dual Activation by Fluoride and In(OTf)3 We thank the National Science Foundation (Vermont EPSCoR) and the University of Vermont for generous support.

A mild, convenient, and stereoselective addition of allylsilanes to enantiopure N-acylhydrazones occurs at room temperature upon complementary activation of both the allylsilane and the hydrazone (see scheme; OTf = trifluoromethanesulfonate). The reaction provides a new mode of acyclic stereocontrol for the asymmetric synthesis of homoallylic amines.