Answers are grounded in this paper and cite their sources.
West Nile Virus (WNV) was immediately and completely inactivated to below assay detection limits upon addition of solvent/detergent (S/D) to intermediate process pools of second and third generation B-domain deleted recombinant Factor VIII (BDDrFVIII; ReFacto, Wyeth, Cambridge, MA, USA). We verify that the S/D step provides robust enveloped virus inactivation (>5 log(10)) and functions as a WNV barrier.
No takes yet. Share an insight, caveat, or question.
Jakubik et al. (2004) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: