Key result
Adenovirus type 41 linked to a kindergarten acute gastroenteritis outbreak with an ~11% attack rate.
Observational (n=122)
No
Adenovirus 41 should be considered in the laboratory protocol for acute gastroenteritis outbreaks in children, even when rotavirus vaccination coverage is high.
Supports including adenovirus 41 in pediatric outbreak diagnostics despite high rotavirus vaccination; leaves open need for broader surveillance.
In response to an alert due to epidemic gastroenteritis in children in a kindergarten, an outbreak investigation was carried out in a Portuguese municipality. The objectives were to establish an aetiological diagnosis, assess vaccine efficacy if possible, and to take corrective measures if necessary. The warden at the kindergarten was interviewed, and we visited the premises. The overall attack rate was 11·4% and most cases were mild. Stool samples from three symptomatic children were collected and screened for the presence of noroviruses, rotaviruses and adenoviruses. High vaccination coverage against rotaviruses was recorded in children aged <2 years. We initially thought that noroviruses and rotaviruses were more likely to have been the aetiological cause of the disease, but the outbreak was caused by infection with adenovirus 41. These viruses should not be overlooked in the laboratory protocol in the study of acute gastroenteritis outbreaks.
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Gonçalves et al. (2010) conducted an observational in Acute gastroenteritis (n=122). Adenovirus type 41 was evaluated on Attack rate of acute gastroenteritis. An outbreak of acute gastroenteritis in a Portuguese kindergarten had an overall attack rate of 11.4% and was identified as being caused by adenovirus type 41.
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