Granuloma faciale is a dermatosis characterized clinically by elevated, usually asymptomatic, reddish-brown plaques on the face. The term granuloma faciale was first used by Pinkus,1to define the lesions in a case he reported with Cobane and Straith.2Formerly this disorder had been termed eosinophilic granuloma of the skin. A study of 15 examples of granuloma faciale has been undertaken at the Armed Forces Institute of Pathology for the purpose of determining its natural history and relation to eosinophilic granulomas and of exploring its histogenesis. Historical Review Eosinophilic Granuloma of the Skin.— The term "eosinophilic granuloma of the skin" was first used in 1937, by Nanta and Gadrat,3in reporting a patient with ulcerating lesions of the mouth and anus associated with tuberculosis. They also reviewed and included in this category a case reported by Freund4and another by
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Waine C. Johnson (1959) studied this question.