Catalyst-Free Synthesis of 2,4-Disubstituted-1 H -imidazoles through [3 + 2] Cyclization of Vinyl Azides with Amidines

A facile and efficient route for the synthesis of 2,4-disubstituted imidazoles from benzimidamides and vinyl azides through [3 + 2] cyclization under catalyst-free conditions has been described. The method is compatible for a broad range of functional groups with good to excellent yields.