The first chloride-containing caryophyllane-type sesquiterpenoid, designated as rumphellatin D (1), was isolated from gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral-data analysis. Rumphellatin D (1) showed moderate inhibitory effects on elastase release by human neutrophils.
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Sung et al. (2008) studied this question.
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