Why the study?
Diabetes mellitus and hypertension are associated with mitochondrial dysfunction and endothelial progenitor cell abnormalities contributing to vascular aging and disease progression.
Observational
p-value: p=< 0.0001
Both diabetes mellitus and hypertension are associated with greater mitochondrial DNA damage and telomere shortening in endothelial progenitor cells, suggesting a mechanism for vascular complications.
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Kartik Gupta (2018) conducted an observational in Diabetes mellitus and hypertension. Diabetes mellitus and/or hypertension vs. Controls without diabetes mellitus or hypertension was evaluated on Mitochondrial DNA damage measured by quantitative PCR (p=< 0.0001).
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