Some Influences of Stilbestrol, Estrone, and Testosterone Propionate on the Genital Tract of Young Female Fowls

ALTHOUGH the estrogenic influence of stilbestrol in mammals is well known, its effect in birds has not been so extensively determined. That it has activity in birds in one manner or another has, however, been demonstrated (Flock and Bollman, 1941; Gaarenstroom, 1939; Mühlbock, 1939; Witschi and Fugo, 1940; Wolff, 1939; and Zondek and Marx, 1939). Experiments were carried out to determine some influences of stilbestrol and other estrogenic and androgenic substances on the genital tracts of young fowls. Single Comb White Leghorn female chicks were used and injections begun when they were 18 days of age. Eleven intramuscular injections were made on alternate days, and all birds were killed on the second clay following the last injection, at which time they were 40 days of age. Upon killing, the genital tracts were severed at the cloaca and removed. The whole genital tracts were weighed, fixed, and the uterine portions sectioned . . .