Key result
Oral dexamethasone for tumor edema linked to atrial fibrillation in a case report.
Case Report (n=1)
This case report highlights the potential for oral dexamethasone to induce atrial fibrillation in a patient treated for post-radiation tumor edema.
May trigger AF after oral dexamethasone; hypothesis-generating case report that leaves causal link open.
Atrial fibrillation (A-fib) is the most common cardiac arrhythmia which is associated with an increased risk of mortality secondary to stroke and coronary artery disease. Intravenous glucocorticoid therapy (such as dexamethasone and hydrocortisone) is frequently used peri-operatively in patients undergoing cardiac surgery to prevent A-fib. Dexamethasone is also frequently used in patients with single or bilateral vestibular schwannomas (VS), to reduce tumor swelling both before and after radiation treatment. We describe a case of A-fib in a 50 year-old female patient with neurofibromatosis type 2 (NF-2), who was prescribed dexamethasone for post-radiation tumor edema.
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Hebb et al. (2014) conducted a case report in Neurofibromatosis type 2 (NF-2) and post-radiation tumor edema (n=1). Oral dexamethasone was evaluated on Atrial fibrillation. Oral dexamethasone treatment for post-radiation tumor edema was associated with the development of atrial fibrillation in a 50-year-old female patient with neurofibromatosis type 2.
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