Key result
Global 2D-strain and strain rate require further study for early cardiotoxicity detection in cancer survivors.
Why the study?
Does 2D strain / 2D strain rate improve the early detection of cardiotoxicity in cancer survivors receiving chemotherapeutic agents?
Does 2D strain / 2D strain rate improve the early detection of cardiotoxicity in cancer survivors receiving chemotherapeutic agents?
2D strain imaging shows potential for early detection of chemotherapy-induced cardiotoxicity, but further investigation is needed to clarify its utility, especially in patients with pre-existing cardiac disease.
Global 2D-strain should not yet guide cardiotoxicity monitoring in cancer survivors; leaves open its utility pending prospective validation.
The cardiac toxicity has been recognized as a major medical problem that negatively affecting quality of life and prognosis in cancer survivors within chemotherapies and after ending of the treatment.The mini review is focused on the innate mechanisms of cardiotoxicity and the techniques regarding the cardiac evaluation of cancer patients.It has discussed radial and circumferential strain rates as a tool for the early detection of cardiotoxicity, whereas there are some limitation to correctly interpret findings in cancer patients with known cardiac disease and heart failure.It is concluded that more investigations are required to explain the advantages and weakness of 2D strain / 2D strain rate in cardiotoxicity determination.
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Alexander Е. Berezin (2016) conducted a review in Cardiotoxicity in cancer survivors. Global 2D-Strain was evaluated. Global 2D-strain and strain rate require further investigation to clarify their utility and limitations for the early detection of cardiotoxicity in cancer survivors.
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