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October 15, 1993Science

Transcription-Coupled DNA Repair

Kevin Sweder Philip C. Hanawalt

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Abstract

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Cite This Study

Sweder et al. (1993) studied this question.

synapsesocial.com/papers/6aa50372ac77d5296f2bd5d2 https://doi.org/10.1126/science.8211165

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Preferential repair of cyclobutane pyrimidine dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription.Original Research · 1992 · 177 citations
2Strand-selective repair of DNA damage in the yeast GAL7 gene requires RNA polymerase IIOriginal Research · 1992 · 133 citations
3Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor.In Vitro Study · 1991 · 114 citations
4Escherichia coli mfd mutant deficient in "mutation frequency decline" lacks strand-specific repair: in vitro complementation with purified coupling factor.Original Research · 1991 · 217 citations
5Molecular Mechanism of Transcription-Repair CouplingOriginal Research · 1993 · 670 citations

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The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.1990
The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair.1994

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