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January 1, 2007Hematology

TTP and ADAMTS13: When Is Testing Appropriate?

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Authors

Pier Mannuccio Mannucci
Pier Mannuccio MannucciUniversità Cattolica del Sacro Cuore
FPFlora PeyvandiBroad Institute

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Mannucci et al. (2007) studied this question.

synapsesocial.com/papers/6aa503e16803e1e7a1f2e50chttps://doi.org/10.1182/asheducation-2007.1.121
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1von Willebrand factor cleaving protease (ADAMTS‐13) and ADAMTS‐13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura2004 · 159 citations
  2. 2ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission2008 · 279 citations
  3. 3The course of ADAMTS‐13 activity and inhibitor titre in the treatment of thrombotic thrombocytopenic purpura with plasma exchange and vincristine2005 · 86 citations
  4. 4Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura2004 · 453 citations
  5. 5Thrombotic thrombocytopenic purpura/haemolytic uraemic syndrome: a new index predicting response to plasma exchange2005 · 66 citations