Key result
Fatal pulmonary thromboembolism autopsies universally reveal fresh DVT, involving the soleal vein in ~91% of limbs.
Observational (n=28)
No
This autopsy study highlights the soleal vein as the most frequent site of deep vein thrombosis and a critical source of fatal pulmonary thromboembolism.
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Soleal vein DVT may underlie most fatal PE; leaves open whether targeted imaging or prophylaxis improves outcomes.
Kageyama et al. (2004) conducted an observational in Fatal pulmonary thromboembolism (n=28). Fatal pulmonary thromboembolism was evaluated on Presence and location of deep vein thrombosis. Deep vein thrombosis containing fresh thrombi was observed in the lower limbs of all 28 autopsy cases with fatal pulmonary thromboembolism, with the soleal vein involved in 91.1% of limbs.
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