Answers are grounded in this paper and cite their sources.
TiCl(4)-promoted multicomponent reactions involving N-tosyl imino ester, cyclic enol ether, and silane reagents in a single one-pot operation provide functionalized alpha-amino acids with multiple stereogenic centers in good to excellent yields. Cis/trans selectivities with optically active substituted dihydrofurans have been investigated.
No takes yet. Share an insight, caveat, or question.
Ghosh et al. (2004) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: