Key result
NSTE-ACS in a 34-year-old pregnant woman reveals a rare transient protein S deficiency.
Why the study?
Myocardial infarction in pregnancy is rare and poses a unique clinical challenge, while the role of coagulation regulatory system deficiencies in arterial thrombosis remains controversial.
Case Report (n=1)
This case report emphasizes the need for a multimodality and multidisciplinary approach to diagnose and manage acute coronary syndrome in pregnant patients with rare coagulopathies like transient protein S deficiency.
Alerts clinicians to rare coagulopathies in pregnant NSTE-ACS; case reports leave open whether targeted testing changes management.
The occurrence of myocardial ischemia and myocardial infarction in pregnancy is relatively rare, the occurrence of myocardial infarction in pregnancy is associated with cardiovascular risk factors. The deficiency of coagulation regulatory systems in the occurrence of venous thrombosis is well established; however, their role in arterial thrombosis is controversial. Here, we present an interesting case of a 34-year-old of acute myocardial syndrome without persistent ST segment elevation, which revealed transient protein S deficiency. Management of acute coronary syndrome (ACS) during pregnancy may represent a unique clinical challenge. In this manuscript, we review the clinical presentation, anatomic considerations, and management strategy in our patient presenting with ACS. Objective: this case highlights the importance of multimodality approach to help to obtain a more timely diagnosis of myocardial infarction in pregnancy and the importance collaboration between obstetricians, cardiologists, pediatricians and anesthesiologists to ensure optimal care.
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Diakité et al. (2019) conducted a case report in Acute myocardial syndrome without persistent ST segment elevation (n=1). Transient protein S deficiency was evaluated. A 34-year-old pregnant woman presented with acute coronary syndrome without persistent ST segment elevation, revealing a rare transient protein S deficiency.
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