An efficient, one-pot synthetic approach to precursors of some new aminochromene/xanthene annulated heterocycles via a tetrabutylammonium hydrogen sulfate–mediated intramolecular domino Knoevenagel–hetero-Diels–Alder reaction is described. The method is general and efficient. The stereochemistry of the product was confirmed by various NMR experiments and single-crystal x-ray diffraction data. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.
No takes yet. Share an insight, caveat, or question.
Parmar et al. (2013) studied this question.