High perioperative stress exposure and traumatic memories in the intensive care unit significantly predicted variations in physical (R2=0.30, p<0.04) and mental (R2=0.52, p<0.01) quality of life.
Cohort (n=148)
No
Does high perioperative stress exposure in the intensive care unit negatively affect health-related quality-of-life outcomes after cardiac surgery?
High perioperative stress and the development of traumatic memories in the cardiovascular ICU are associated with worse physical and mental health-related quality of life 6 months after cardiac surgery.
p-value: p=<.04
OBJECTIVE: Up to 20% of patients do not show improvements in health-related quality of life (HRQL) after cardiac surgery, despite apparently successful surgical procedures. We sought to determine whether failed improvements in HRQL after cardiac surgery are associated with the development of traumatic memories and chronic stress states as a result of high perioperative stress exposure. DESIGN: Prospective cohort study. SETTING: A 10-bed cardiovascular intensive care unit of a tertiary care university hospital. PATIENTS: A total of 148 cardiac surgical patients. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The patients were evaluated for traumatic memories from postoperative treatment in the cardiovascular intensive care unit (defined as the subjective recollection of pain, respiratory distress, anxiety/panic, and nightmares), symptoms of chronic stress, including those of posttraumatic stress disorder, and HRQL preoperatively (at baseline) and at 6 months after cardiac surgery. A state of chronic stress was defined as the development of posttraumatic stress disorder at 6 months after surgery. Factors predicting the decline in HRQL were determined by multivariable linear regression. Twenty-seven patients (18.2%) had posttraumatic stress disorder at 6 months after cardiac surgery; seven of these patients (4.8%) had evidence of preexisting posttraumatic stress disorder before undergoing cardiac surgery. Patients with new posttraumatic stress disorder at 6 months after cardiac surgery had a significantly higher number of traumatic memories from postoperative treatment in the cardiovascular intensive care unit (p =.01). A multiple regression model included the number of traumatic memories from the intensive care unit and stress symptom scores at 6 months after heart surgery as predictors for variations in physical HRQL outcome scores (R2 =.30, p <.04). Stress symptom scores were the most significant predictors of mental health HRQL outcomes (R2 =.52, p <.01). CONCLUSIONS: Exposure to high stress in the cardiovascular intensive care unit can have negative effects on HRQL outcomes of cardiac surgery.
Schelling et al. (2003) conducted a cohort in Cardiac surgery (n=148). High perioperative stress exposure was evaluated on Variations in physical and mental health HRQL outcome scores (p=<.04). High perioperative stress exposure and traumatic memories in the intensive care unit significantly predicted variations in physical (R2=0.30, p<0.04) and mental (R2=0.52, p<0.01) quality of life.