Key result
Persistent PVCs are linked to poor prognosis in primary myocardial disease, unlike excess alcohol intake.
Cohort (n=50)
In patients with primary myocardial disease and heart failure, the disease course is persistent, and persistent premature ventricular contractions indicate a poor prognosis.
Persistent PVCs may indicate poor prognosis in primary myocardial disease; hypothesis-generating for arrhythmia-focused trials.
Fifty patients with primary myocardial disease have been followed up for a mean period of 2½ years following their initial episode of congestive heart failure. Once heart failure occurred, myocardial disease has been persistent. Excess alcohol intake was common but not universal, and its precise role in the pathogenesis of this syndrome remains uncertain; it does not appear to be a major influence on the clinical features or course of patients in this study. Return of the heart size to normal has generally not resulted in maintenance of normal size and has not beneficially influenced the prognosis. Persistent premature ventricular contractions proved to be a bad prognostic sign.
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G. I. Shugoll (1972) conducted a cohort in Primary myocardial disease (n=50). Persistent premature ventricular contractions was evaluated on Prognosis and clinical course. Persistent premature ventricular contractions were a poor prognostic sign in patients with primary myocardial disease, whereas excess alcohol intake had no major influence on the clinical course.
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