Synthesis and Antibacterial Activity of Some Oxazolone Derivatives

일련의 옥사졸론 유도체들을 (4a-n) 항균제로서 합성하였다. 이 화합물들은 아릴옥시아세틸아미노아세트산을 에탄올, 아세트산 무수물, 아세트산 소듐 존재하에 알데하이드와 반응시켜 합성하였으며 핵자기공명 스펙트럼과 적외선 스펙트럼으로 구조를 확인하였다. A series of oxazolone derivatives (4a-n) have been synthesized as a potential antibacterial agent. Titled compounds have been prepared by the condensation of aryloxy acetyl-amino-acetic acid with aldehyde in presence of ethanol, acetic anhydride and sodium acetate. The structures of the new compounds were established on the basis of ¹H NMR and IR spectral data.