Key result
Parental hypertension linked to ~12 mmHg higher SBP immediately after isometric handgrip exercise.
Why the study?
Hypertension must be detected early to initiate preventive measures, and the study aimed to evaluate the risk of inherited hypertension in medical students with hypertensive parents using cardiovascular responses to isometric handgrip exercise.
Does isometric hand grip exercise reveal exaggerated cardiovascular responses in normotensive young adults with hypertensive parents compared to those with normotensive parents?
Cross-Sectional (n=50)
No
Does isometric hand grip exercise reveal exaggerated cardiovascular responses in normotensive young adults with hypertensive parents compared to those with normotensive parents?
Absolute Event Rate: 136.2% vs 124.4%
p-value: p=<0.001
Normotensive young adults with a family history of hypertension show exaggerated cardiovascular responses to isometric exercise, indicating early autonomic dysregulation and potential future risk of hypertension.
May indicate familial predisposition to exaggerated pressor responses; hypothesis-generating and should not yet change practice.
Background: Hypertension is one of the most powerful risk factors for cardiovascular disease. This biggest health challenge has to be detected early so that preventive measures can be taken for the susceptible population. Increased cardiovascular stress responsivity with sustained isometric muscle contraction is associated with cardiovascular disease. So this isometric handgrip exercise is a simple, non-invasive screening test to assess the risk of development of hypertension in future. Aim and objective of the study was to identify the chance of inheritance of hypertension in medical students of hypertensive parents. Methods: After getting ethical committee approval, in this cross sectional study, 50 medical students of Government Sivagangai Medical college with normotensive and hypertensive parents were selected. Heart rate (bpm) and blood pressure (mmHg) before, immediately and 5 minutes after isometric hand grip exercise using hand grip dyanamometer in both the groups. Results: Statistical analysis of the values among the participants was done by student t-test using statistical package for the social sciences (SPSS) version 11.0.and the results were compared between the study and control groups. A ‘p’ value of <0.05 is considered significant. Cardiovascular responses are found to be significantly higher in study group (p<0.001). Conclusions: Early and regular screening of the students with hypertensive parents is necessary to prevent cardiovascular complications in future by emphasizing the life style modifications.
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Malarvannan et al. (2023) conducted a cross-sectional in Family history of hypertension (n=50). Family history of hypertension vs. Normotensive parents was evaluated on Systolic blood pressure immediately after isometric hand grip exercise (mmHg) (p=<0.001). Medical students with hypertensive parents exhibited significantly higher systolic blood pressure immediately after isometric handgrip exercise compared to those with normotensive parents (136.2 vs 124.4 mmHg, p<0.001).
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