Key result
Feline extraocular muscle blood flow exceeds all other skeletal muscles, ranking second only to myocardium.
Extraocular muscles in cats have exceptionally high blood flow, exceeded only by the myocardium, likely due to high constant activity during wakefulness.
High extraocular muscle blood flow in cats warrants caution in human extrapolation; leaves open mechanistic studies in ocular motility disorders.
Fractional blood flow was measured and absolute blood flow calculated in the six extraocular muscles of the quiet, alert cat by the isotope dilution method. Absolute blood flow ranged from 51.8 ml/ min/100 gm muscle in the superior oblique to 78.2 ml/min/100 gm muscle in the superior rectus. Average blood flow in the six extraocular muscles exceeded that of all other skeletal muscles examined and was exceeded only by myocardium. The high constant level of activity in extraocular muscle during wakefulness appeared to be a determinant factor in the maintenance of high extraocular muscle blood flow.
No takes yet. Share an insight, caveat, or question.
Wooten et al. (1972) studied Quiet, alert cats (animal study). Wakefulness vs. Other skeletal muscles and myocardium was evaluated on Absolute blood flow in extraocular muscles. Absolute blood flow in the extraocular muscles of quiet, alert cats ranged from 51.8 to 78.2 ml/min/100 gm, exceeding all other skeletal muscles examined and second only to myocardium.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: