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June 1, 1997International ImmunologyOpen Access

The thymus and self-tolerance: co-existence of encephalitogenic S100 beta-specific T cells and their nominal autoantigen in the normal adult rat thymus

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KKKatsura KojimaNational Agriculture and Food Research Organization

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Katsura Kojima (1997) studied this question.

synapsesocial.com/papers/6aa53b2f041e43fea73a4de2https://doi.org/10.1093/intimm/9.6.897
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.1992 · 721 citations
  2. 2Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.1987 · 1,179 citations
  3. 3Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells.1995 · 147 citations