Why the study?
Is there an association between obstructive sleep apnoea and endothelial dysfunction?
Is there an association between obstructive sleep apnoea and endothelial dysfunction?
This letter raises statistical concerns regarding a previous study linking obstructive sleep apnea to endothelial dysfunction.
To the Editor I read with interest the cross-sectional study by Namtvedt et al 1 for 77 adults who were sampled from 30 000 individuals aged 30–65 years. They concluded that there was a significant positive association between obstructive sleep apnoea (OSA) and endothelial dysfunction by using indicators of apnoea–hypopnoea index (AHI), flow-mediated dilatation (FMD), sex and some cardiovascular risk factors. Atkinson made a query on the validity of FMD on their study,2 and I present some statistical concerns …
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Tomoyuki Kawada (2013) conducted a letter in Obstructive sleep apnoea (n=77). Obstructive sleep apnoea (OSA) was evaluated on Endothelial dysfunction (flow-mediated dilatation).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: