The bleeding time (Ivy method) was, however, normal in all 23 patients studied.None of the patients in this small series was thrombocytopenic.It is unlikely that this acquired platelet funotion defect will be of clinical significance, but until further experience is gained with this agent it would seem advisable to measure the bleeding time and platelet count before major surgery in patients taking sodium valproate.
No takes yet. Share an insight, caveat, or question.
Bengt Möller (1976) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: