Letter: Cholestyramine and diabetic post-vagotomy diarrhoea.

had a good initial response to tetracosactrin and those who did not, nor indeed between those with a low level of circulating plasma cortisol and those with a normal level.It is interesting, however, that the one patient who did show signs of a major complication during the attempted substitution had both a low level of plasma cortisol and a very poor response to tetracosactrin.Another observation which we feel is worth making is that all our patients' asthma was well controlled on a maintenance dosage of iprednisone before we attempted substitution with beclomethasone dipro- pionate.We have found that it is extremely difficult, if not impossible, to make this substitution if the asthma is not weU con- trolled initially by corticosteroids admiinistered other than 'by inihalation.-Weare, etc.,