The Prognostic Implication of Late Gadolinium Enhancement Quantification and Syncope in Hypertrophic Cardiomyopathy

Figures

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  Figure A1. Kaplan–Meier curves and the corresponding event rates for (A) the composite of new-onset VT, appropriate ICD therapy, and all-cause mortality; (B) new-onset VT; and (C) appropriate ICD therapy and all-cause mortality stratified by the presence of significant LVOT obstruction. ICD, implantable cardioverter defibrillator; LVOT, left ventricular outflow tract; VT, ventricular tachycardia.

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  Figure A2. Kaplan–Meier curves and the corresponding event rates for (A) the composite of new-onset VT, appropriate ICD therapy, and all-cause mortality; (B) new-onset VT; (C) appropriate ICD therapy and all-cause mortality stratified by an ESC-HCM-SCD risk score cut-off of 6%. ICD, implantable cardioverter defibrillator; VT, ventricular tachycardia.

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  Figure 1. Different amounts of late gadolinium enhancement (LGE) with (A) no LGE, (B) only traces (< 5%) of LGE, and (C) massive (> 15%) LGE.

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  Figure 2. Kaplan–Meier curves and the corresponding event rates for (A) the composite of new-onset VT, appropriate ICD therapy, and all-cause mortality; (B) new-onset VT; and (C) appropriate ICD therapy and all-cause mortality stratified by LGE cut-off of 5%. ICD, implantable cardioverter defibrillator; LGE, late gadolinium enhancement; VT, ventricular tachycardia.

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  Figure 3. Kaplan–Meier curves and the corresponding event rates for (A) the composite of new-onset VT, appropriate ICD therapy, and all-cause mortality; (B) new-onset VT; and (C) appropriate ICD therapy and all-cause mortality stratified by the presence of syncope. ICD, implantable cardioverter defibrillator; VT, ventricular tachycardia.

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  Figure 4. Relationship between LGE as a continuous variable, LGE cut-off of 5%, syncope, and outcomes. Cox regression models were adjusted for age, sex, creatinine, diabetes, heart failure, coronary artery disease, hypertension, atrial fibrillation, LVOT gradient, and interventricular septum thickness. ICD, implantable cardioverter defibrillator; LGE, late gadolinium enhancement; LVOT, left ventricular outflow tract; VT, ventricular tachycardia.

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  Figure 5. Kaplan–Meier curves and the corresponding event rates for (A) the composite of new-onset VT, appropriate ICD therapy, and all-cause mortality, (B) new-onset VT, and (C) appropriate ICD therapy and all-cause mortality by the presence of syncope and by LGE cut-off of 5%. ICD, implantable cardioverter defibrillator; LGE, late gadolinium enhancement; VT, ventricular tachycardia.