Endoscopic Molecular Imaging: Beacon to the Destination

Imaging technologies in gastrointestinal endoscopy have advanced greatly over the past few decades. Molecular imaging may be an additional innovation to conventional imaging methods and allow visualization of the localization, function, and characteristics of targets, especially in cancers. To realize endoscopic molecular imaging, there are three prerequisites: first, more target‐specific and highly sensitive biomarkers for clinical use; second, fluorochromes that have a high affinity to the markers and can produce a distinct signal; and third, equipment to visualize the indicator at high resolution in real time. This technique can be used for cancer screening and surveillance and can also provide important information for deciding treatment strategies and evaluating their effectiveness during therapy. Endoscopic molecular imaging will play a central role in gastrointestinal oncology in the near future.