Key result
MRI detects pyramidal tract wallerian degeneration in ~46% of patients with internal capsule ischemic infarction.
Why the study?
Can magnetic resonance imaging detect wallerian degeneration of the pyramidal tract in patients with ischemic infarction of the internal capsule?
Observational (n=24)
Can magnetic resonance imaging detect wallerian degeneration of the pyramidal tract in patients with ischemic infarction of the internal capsule?
MRI can effectively detect wallerian degeneration of the pyramidal tract in patients with capsular infarction, particularly when associated with motor deficits and posterior limb lesions.
MRI identifies wallerian degeneration after capsular infarct; leaves open its prognostic value pending prospective validation.
Using magnetic resonance imaging, we studied 24 patients with ischemic infarction of the internal capsule. Magnetic resonance imaging detected wallerian degeneration of the pyramidal tract below the capsular lesion in 11 patients (45.8%); all 11 had clinical evidence of pyramidal tract damage. In six additional patients magnetic resonance imaging findings, present only on axial slices, were considered to indicate possible wallerian degeneration. When motor deficit was associated with posterior limb lesions, magnetic resonance imaging detected wallerian degeneration of the pyramidal tract in 78.6% (11) of 14 patients.
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Martí-Vilalta et al. (1990) conducted an observational in Ischemic infarction of the internal capsule (n=24). Magnetic resonance imaging was evaluated on Detection of wallerian degeneration of the pyramidal tract below the capsular lesion. Magnetic resonance imaging detected wallerian degeneration of the pyramidal tract in 45.8% of patients with ischemic infarction of the internal capsule.
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