Key result
Oseltamivir and temporary pacing rescue a pregnant woman with influenza A myocarditis and cardiogenic shock.
Why the study?
Influenza infection can rarely be complicated by acute myocarditis leading to high-degree atrioventricular block and cardiogenic shock.
Case Report (n=1)
Influenza myocarditis can present with high-degree AV block and cardiogenic shock in pregnant women, which can be successfully managed with antiviral therapy and temporary pacing.
Alerts clinicians to rare influenza myocarditis with AV block in pregnancy; leaves open need for incidence and management data.
Acute myocarditis is a well-recognized complication of influenza infection. The incidence of myocardial involvement in influenza infection is variable, and the clinical severity can range from asymptomatic to fulminant forms. Influenza infection can rarely be complicated by acute myocarditis leading to high-degree atrioventricular block and cardiogenic shock. We report a previously healthy pregnant woman, who initially presented with symptoms of influenza-like illness, later confirmed as influenza A infection. She developed hypotension shortly after admission that did not respond to fluid bolus and required inotropic support. On day 5, the electrocardiogram showed Mobitz I second-degree heart block, which later progressed to the third-degree heart block. Echocardiogram showed good cardiac contractility and minimal pericardial effusion while cardiac biomarkers were normal. A diagnosis of influenza myocarditis was made. She completed a course of oral oseltamivir and had temporary cardiac pacing performed, and subsequently recovered well.
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Chang et al. (2020) conducted a case report in Influenza myocarditis complicated with atrioventricular block (n=1). Oral oseltamivir and temporary cardiac pacing was evaluated. A pregnant woman with influenza A myocarditis complicated by third-degree heart block and cardiogenic shock successfully recovered following treatment with oral oseltamivir and temporary cardiac pacing.
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