Key result
Drug-induced thrombocytopenic purpura linked to subendocardial MI and diffuse hemorrhages in two cases.
Case Report (n=2)
Abnormal haemostasis in thrombocytopenia might induce diffuse myocardial damage, highlighting the potential utility of serial electrocardiograms in thrombocytopenic patients.
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May suggest myocardial injury risk in thrombocytopenia; hypothesis-generating and requires confirmation before any monitoring change.
Two female patients who suffered from drug-induced thrombocytopenic purpura and subendocardial myocardial infarction are presented. One of them died from cerebral haemorrhage and diffuse subendocardial punctate haemorrhages were found at post-mortem. The abnormal haemostasis which is associated with thrombocytopenia might induce diffuse damage of the myocardium and might impair heart performance. This finding may be more frequent than hitherto appreciated and calls for serial electrographic tracings in thrombocytopenic patients.
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Fireman et al. (1979) conducted a case report in Drug-induced thrombocytopenic purpura and subendocardial myocardial infarction (n=2). Drug-induced thrombocytopenic purpura was evaluated. Drug-induced thrombocytopenic purpura was associated with subendocardial myocardial infarction and diffuse subendocardial punctate haemorrhages in two female patients.
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