Key result
Enhanced external counterpulsation therapy significantly reduced ESV and EDV and increased LVEF in patients with baseline LVEF ≤ 50% (P=.018, .013, .002), but not in those with LVEF >50%.
Why the study?
Does enhanced external counterpulsation (EECP) therapy improve echocardiographic measures of systolic and diastolic cardiac function?
Does enhanced external counterpulsation (EECP) therapy improve echocardiographic measures of systolic and diastolic cardiac function?
EECP therapy improves echocardiographic parameters of systolic and diastolic function specifically in patients with baseline left ventricular dysfunction.
This study assessed the effects of a course of enhanced external counterpulsation (EECP) therapy on systolic and diastolic cardiac function using echocardiography to measure left ventricular ejection fraction (LVEF), end-systolic volume (ESV), end-diastolic volume (EDV), systolic wave (Sm), early diastolic wave (Ea), Vp, E/Ea, E/Vp, and diastolic function grade in 25 patients before and after 35 hours of EECP. EECP reduced ESV and EDV and increased ejection fraction significantly in patients with baseline LVEF < or = 50% (P=.018, .013, .002), baseline E/Ea > or = 14 (P=.032, .038, .007), baseline grade II or III diastolic dysfunction (decreased compliance) (P=.014, .032, .027), baseline Ea <7 cm/s (P=.015, .024, .001), and baseline Sm <7 cm/s (P=.017, .016, .006), but not in patients with baseline LVEF >50%, baseline E/Ea <14, baseline normal diastolic function or grade I diastolic dysfunction (impaired relaxation), baseline Ea > or = 7 cm/s, and Sm > or = 7 cm/s. These results demonstrate improved systolic and diastolic function in selected patients and provide new insight into potential clinical applications of EECP.
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Estahbanaty et al. (2007) studied this question. Enhanced external counterpulsation (EECP) therapy vs. Baseline (before therapy) was evaluated on Systolic and diastolic cardiac function (including LVEF, ESV, EDV) (p=P=.018, .013, .002). Enhanced external counterpulsation therapy significantly reduced ESV and EDV and increased LVEF in patients with baseline LVEF ≤ 50% (P=.018, .013, .002), but not in those with LVEF >50%.
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