// Tongtong Ge 1, * , Wei Yang 1, * , Jie Fan 1 and Bingjin Li 1 1 Jilin Provincial Key Laboratory on Molecular and Chemical Genetics, The Second Hospital of Jilin University, Changchun 130041, PR China * These authors contributed equally to this work Correspondence to: Bingjin Li, email: libingjin@jlu.edu.cn Keywords: ghrelin, epilepsy, hippocampus, memory, neuroprotection Received: March 08, 2017 Accepted: May 22, 2017 Published: June 02, 2017 ABSTRACT Ghrelin, an orexigenic peptide synthesized by endocrine cells of the gastric mucosa, plays a major role in inhibiting seizures. However, the underlying mechanism of ghrelin’s anticonvulsant action is still unclear. Nowadays, there are considerable evidences showing that ghrelin is implicated in various neurophysiological processes, including learning and memory, neuroprotection, neurogenesis, and inflammatory effects. In this review, we will summarize the effects of ghrelin on epilepsy. It may provide a comprehensive picture of the role of ghrelin in epilepsy.
No takes yet. Share an insight, caveat, or question.
Ge et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: