Key result
Thoracoscopic mini-Maze achieves normal sinus rhythm in ~90% of medically refractory AF patients.
Why the study?
Does the thoracoscopic mini-Maze procedure improve sinus rhythm maintenance in patients with atrial fibrillation?
Observational (n=20)
Yes
Does the thoracoscopic mini-Maze procedure improve sinus rhythm maintenance in patients with atrial fibrillation?
The thoracoscopic mini-Maze procedure demonstrates high short-term efficacy for maintaining sinus rhythm in atrial fibrillation, though perioperative bleeding complications highlight the need for further procedural refinement.
May support feasibility in refractory AF; leaves open need for randomized trials before practice change.
BACKGROUND: The cut-and-sew Maze procedure has historically been the most efficacious therapy for patients with atrial fibrillation (AF) that is refractory to medical management, but is not widely used as a stand-alone treatment for AF. New ablation technologies can create pulmonary vein (PV) isolation without cardiopulmonary bypass. METHODS AND RESULTS: The 'thoracoscopic mini-Maze' procedure includes bilateral PV isolation, ablation of the epicardial ganglionated plexi and excision of the left atrial appendage using small bilateral thoracotomies with thoracoscopic assistance. Between January 2006 and April 2007, 20 thoracoscopic mini-Maze procedures were performed at 2 institutions and over a mean follow-up of 16.6 months, 18 (90%) patients are in sinus rhythm. Perioperative bleeding complications occurred in 3 patients (15%) and there was 1e (5%) late instance of atrial flutter that required a right-sided ablation. None of the patients died or needed a pacemaker. CONCLUSIONS: Early experience with the thoracoscopic mini-Maze procedure suggests that sinus rhythm can be re-established in most patients in the short-term and with more experience the rate of complications should reduce, which is required prior to defining the role of this therapy in the future treatment of AF.
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Matsutani et al. (2008) conducted an observational in Atrial fibrillation (n=20). Thoracoscopic mini-Maze procedure was evaluated on Normal sinus rhythm (freedom from atrial fibrillation). The thoracoscopic mini-Maze procedure successfully re-established normal sinus rhythm in 90% of patients with medically refractory atrial fibrillation over a mean follow-up of 16.6 months.
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