Key result
Combination chemotherapy resolves pulmonary artery pseudoaneurysms in two patients with lung squamous cell carcinoma.
Case Report (n=2)
No
Small, well-encased pseudoaneurysms due to squamous cell carcinoma of the lung may resolve with chemotherapy alone without requiring invasive intervention.
May allow non-invasive management in select cases; hypothesis-generating and requires prospective validation.
Pseudoaneurysm due to cancer is uncommon generally and is extremely rare in lung cancer. We report two cases of false aneurysms due to lung cancer that spontaneously regressed upon chemotherapy without intervention. Both patients had squamous cell carcinoma of the lung and the diagnosis of a pseudoaneurysm was made using computed tomography. There was no evidence of severe bronchial hemorrhage and the pseudoaneurysms were small and well-encased. Chemotherapy was performed and the pseudoaneurysms resolved.
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Kim et al. (2009) conducted a case report in Pseudoaneurysm due to squamous cell carcinoma of the lung (n=2). Combination chemotherapy (docetaxel and cisplatin) was evaluated on Resolution of pseudoaneurysm. Combination chemotherapy with docetaxel and cisplatin led to the spontaneous resolution of pulmonary artery pseudoaneurysms in two patients with squamous cell carcinoma of the lung.
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