Answers are grounded in this paper and cite their sources.
We report chorea in an infant with holoprosencephaly. Congenital structural brain disease has not been a reported cause of chorea. Cranial magnetic resonance imaging revealed small, fused frontal lobes with hypoplastic caudates. Our patient responded to symptomatic treatment with dopamine-depleting agents. It is likely that the mechanism for the chorea was a dysfunction of the striatum. The differential diagnosis of childhood chorea should include holoprosencephaly.
No takes yet. Share an insight, caveat, or question.
Louis et al. (1995) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: