Key result
VMS3.0+ strongly correlates with Tomtec for 3D echo LA and LV volumes while reducing analysis time.
Why the study?
Three-dimensional echocardiography is an emerging method for volumetric cardiac measurements, but few vendor-neutral analysis packages exist.
Does the Ventripoint Medical System Plus (VMS3.0+) algorithm correlate with the TomTec 3D echocardiogram algorithm in measuring left cardiac chamber volumes in pediatric patients?
Observational (n=98)
Does the Ventripoint Medical System Plus (VMS3.0+) algorithm correlate with the TomTec 3D echocardiogram algorithm in measuring left cardiac chamber volumes in pediatric patients?
Effect estimate: ICC 0.91 (95% CI 0.78-0.96)
The knowledge-based VMS3.0+ algorithm provides comparable volumetric measurements to the established Tomtec software in pediatric patients, while requiring less analysis time.
May reduce analysis time for pediatric 3D echo volumetry; leaves open prospective validation before routine adoption.
BACKGROUND: Three-dimensional echocardiography (3DE) is an emerging method for volumetric cardiac measurements; however, few vendor-neutral analysis packages exist. Ventripoint Medical System Plus (VMS3.0+) proprietary software utilizes a validated Magnetic resonance imaging (MRI) database of normal ventricular and atrial morphologies to calculate chamber volumes. This study aimed to compare left ventricular (LV) and atrial (LA) volumes obtained using VMS3.0+ to Tomtec echocardiography analysis software. METHODS: Healthy controls (n = 98) aged 0-18 years were prospectively recruited and 3D DICOM datasets focused on the LV and LA acquired. LV and LA volumes and ejection fractions were measured using TomTec Image Arena 3D LV analysis package and using VMS3.0+. Pearson correlation coefficients, Bland-Altman's plots, and intraclass coefficients (ICC) were calculated, along with analysis time. RESULTS: = .88, ICC .91 [95% CI .78, .96]) volumes on linear regression models. Natural log transformations eliminated heteroscedasticity, and power transformations provided the best fit. The time (mins) to analyze volumes using VMS were less than using Tomtec (LV VMS 2.3 ± .5, Tomtec 3.3 ± .8, p < .001; LA: VMS 1.9 ± .4, Tomtec 3.4 ± 1.0, p < .001). CONCLUSIONS: There was a very good correlation between knowledge-based (VMS3.0+) and 3D (Tomtec) algorithms when measuring 3D echocardiography-derived LA and LV volumes in pediatric patients. VMS was slightly faster than Tomtec in analyzing volumetric measurements.
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Ahmad et al. (2022) conducted an observational in Healthy controls (n=98). Ventripoint Medical System Plus (VMS3.0+) vs. Tomtec echocardiography analysis software was evaluated on Left ventricular and atrial volumes and analysis time (ICC 0.91, 95% CI 0.78-0.96). VMS3.0+ showed very good correlation with Tomtec for measuring 3D echocardiography-derived LA and LV volumes (ICC 0.91; 95% CI 0.78-0.96) and required less analysis time (P<0.001).
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