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Previous studies have suggested an important role for interleukin-15 (IL-15) in resistance to and memory for Toxoplasma gondii infection. The studies presented here reveal that IL-15 is not required for infection-induced expansion of NK or CD8+ T cells. Furthermore, IL-15-/- mice develop long-term protective immunity to this pathogen.
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Lieberman et al. (2004) studied this question.
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