Key result
Dabigatran prevents thrombosis but requires careful perioperative management given reduced renal clearance and no reversal.
Population
Elective and emergency surgical patients on dabigatran therapy
Design
Review
Authors
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May guide dabigatran perioperative care; leaves open prospective validation of hemorrhage protocols.
This review provides practical clinical advice on the perioperative management of surgical patients on dabigatran and guidelines for managing acute hemorrhage.
Breik et al. (2013) conducted a review in Thromboprophylaxis in surgical patients. Dabigatran was evaluated. Dabigatran provides effective thromboprophylaxis but requires careful perioperative management due to reduced clearance in renal failure and the lack of an effective reversing agent.
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