Pharmacoepidemiology and Risk Factors assessment of Metabolic Syndrome in Geriatric Patients Admitted at Tertiary Care Hospital – A Cross-Sectional study

Introduction: Metabolic syndrome (Mets) is the major threat factor for morbidity and mortality in geriatric patients. Cardiovascular diseases are the major complications and early detection, proper treatment, management help to improve quality of life. So, this study is to evaluate the risk components, risk behaviors, use, and effects of drugs for metabolic syndrome in the geriatric population. Methods: This was a prospective cross-sectional investigation done for a duration of 6 months. Totally, 340 both male and female patients of age above 65 were enrolled. Ethical approval was obtained from MIMS, Mandya. The south asian diagnostic criteria were used in our study. Details such as demographics, threat factors, diagnosis, lab values, past and present medical conditions, past and present medications were collected and subjected to statistical analysis.Results: Among 340 patients, male patients (57%) are more admitted in hospital. Based on diagnostic criteria majority of patients having three components (67%). Major threat factors are smoking (OR=27.5), family history (OR=2) and alcohol consumption (OR=1.38). Metformin, amlodipine and atorvastatin were commonly using for the management of risk components. The ANOVA results was found to be 0.00 for hyperglycaemia and 0.007 for hypertension in relation to gender wise distribution. Conclusion: Our study concludes that male patients were more suffering from metabolic syndrome. Both Modifable and non-modifable risk factors influencing the metabolic syndrome. Therapeutic efficacy of drugs are also depends on threat factors. So, Proper education, drug selection and healthy life style practices helps to prevent complications, improve drug efficacy and quality of life.