Why the study?
Predictive tests for coronary angiographic results set the basis for earlier monitoring before additional complications become obvious in a country with high coronary heart disease mortality.
Cross-Sectional (n=124)
No
Clinical and biochemical parameters, including ethnicity, diabetes, fasting blood sugar, NT-proBNP, creatinine, and HbA1c, are significantly associated with angiographic CAD severity in Trinidadian patients.
Anthropometric and biochemical parameters may correlate with angiographic CAD in Trinidad; leaves open incremental predictive value beyond standard risk models.
Background Trinidad and Tobago ranks number 45 in the world for total deaths due to coronary heart disease. Predictive tests for coronary angiographic results set the basis for earlier monitoring of the disease before additional complications become obvious. Aims and Methods This study aimed to evaluate the anthropometric and biochemical parameters of 124 patients with suspected coronary artery disease (CAD) in Trinidad and how these parameters correlate to the findings at angiography. Results The biochemical parameters showed statistically significant correlations with CAD severity by Spearman's rank-order correlation. Two clinical parameters showed significant associations with CAD severity—ethnicity (χ2 (4) = 12.925, p = 0.012) and presence of type 2 diabetes at baseline (χ2 (4) = 21.483, p < 0.001). Conclusion Biochemical parameters such as fasting blood sugar, N-terminal pro B-type natriuretic peptide, creatinine, and hemoglobin A1c were well correlated and well associated with the severity of CAD after diagnosis by the process of coronary angiography. Hence, these factors can be taken into consideration to predict the severity of CAD.
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Nayak et al. (2023) conducted a cross-sectional in Suspected coronary artery disease (n=124). Type 2 diabetes and biochemical markers vs. Patients without Type 2 diabetes / lower biomarker levels was evaluated on Presence of coronary artery disease (OR 5.182, 95% CI 1.086-9.548, p=0.024).
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