A rare case of parasomnia associated with Micronized Progesterone Therapy

Micronized progesterone is commonly prescribed to manage hormonal imbalances and gynecological conditions, such as endometriosis. While its sedative effects are well-documented, the occurrence of parasomnias as an adverse effect is rare. This case documents a 48-year-old woman who developed complex parasomnia behaviors shortly after initiating micronized progesterone therapy. The symptoms resolved upon discontinuing the medication, suggesting a probable causal relationship. This case highlights the need for clinicians to be aware of potential sleep-related side effects associated with progesterone therapy.